检验医学与临床Issue(12)：1676-1677,1680,3.DOI:10.3969/j.issn.1672-9455.2015.12.007
血清人附睾蛋白4、糖类抗原153在监测术后乳腺癌复发转移的探讨
The value of the HE4 and CA153 to breast cancer patients with recurrence and metastasis
摘要
Abstract
Objective To explore the human epididymis protein‐4 (HE4) and CA153 in the patients for post‐operative with recent breast cancer and many years and recurrence ,metastasis ,and anlyze correlation analysis of the HE4 and CA153 in the serum of breast cancer patients .Methods HE4 and CA153 were detected in the health group、postoperative breast cancer without metastasis and postoperative breast cancer with recurrence and metastasis group by using the Roche electro chemiluminescence immunoassay analyzer E170 .Results Compared with health group and the postoperative breast cancer without metastasis group ,HE4 ,CA153 were obviously increased in the pa‐tients with breast cancer recurrence and metastasis(P<0 .05);The positive rates for HE4 and CA153 were obviously increased in the patients with breast cancer recurrence and metastasis(P<0 .05);Compared with health group ,HE4 and the positive rates were obviously increased in the postoperative breast cancer without metastasis(P<0 .05) ,and CA153 was obviously increased(P<0 .05) ,and the positive rate for CA153 without difference(P<0 .05);In addi‐tion ,the correlation of HE4 and CA153 in the patients for postoperative breast cancer was good ,and the correlation coefficient was 0 .607 ,P=0 .000 .Conclusion HE4 and CA153 play an important role in monitoring the recurrence and metastasis of postoperative breast cancer .关键词
人附睾蛋白E4/糖类抗原153/乳腺癌/术后Key words
human epididymis secretory protein E4/CA153/breast cancer/postoperative引用本文复制引用
郭变琴,吴立翔..血清人附睾蛋白4、糖类抗原153在监测术后乳腺癌复发转移的探讨[J].检验医学与临床,2015,(12):1676-1677,1680,3.基金项目
重庆市自然科学基金（cstc2014jcyjA10106）。 （）
