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三种脂蛋白与冠心病及冠状动脉狭窄程度的相关性研究

肖立 林杰 孔维菊 陈力平

检验医学与临床Issue(12):1723-1724,2.
检验医学与临床Issue(12):1723-1724,2.DOI:10.3969/j.issn.1672-9455.2015.12.025

三种脂蛋白与冠心病及冠状动脉狭窄程度的相关性研究

Study on the correlation between three types of lipoprotein and coronary heart disease and the severity of coronary artery stenosis

肖立 1林杰 1孔维菊 1陈力平1

作者信息

  • 1. 中国人民解放军第101医院检验科,江苏无锡 214044
  • 折叠

摘要

Abstract

Objective To explore the correlation of the high density lipoprotein ,low density lipoprotein ,low density lipoprotein with coronary heart disease and the degree of coronary stenosis .Methods 60 cases of coronary heart disease patients as study group ,and 30 non coronary heart disease patients as control group .clinical data ,three types of lipoprotein levels were Compard in two groups of patients and coronary stenosis degree was analyzed by Gensini score .Results The high density lipoprotein levels in the study group were significantly higher than those in the control group (P<0 .01) ,low density lipoprotein cholesterol and low density lipoprotein levels were significantly higher than those in the control group (P<0 .01) .Logistic regression analysis showed that high density lipoprotein , low density lipoprotein and low density lipoprotein levels independently associated with coronary artery disease (P<0 .05) .Small dense low density lipoprotein level and Gensini score of positive correlation (r=0 .670 ,P<0 .01) ,high density lipoprotein cholesterol level is negatively correlated with the Gensini score (r= -0 .374 ,P<0 .05) ,low den‐sity lipoprotein no correlation with Gensini score (r=0 .256 ,P>0 .05) .Conclusion patients with coronary heart dis‐ease and three kinds of lipoprotein levels in patients with coronary heart disease were independently associated with coronary artery disease ,but only for high density lipoprotein and small dense low density lipoprotein levels related to coronary stenosis .

关键词

高密度脂蛋白/低密度脂蛋白/冠心病/冠状动脉狭窄

Key words

high density lipoprotein/low density lipoprotein/coronary heart disease/coronary artery stenosis

引用本文复制引用

肖立,林杰,孔维菊,陈力平..三种脂蛋白与冠心病及冠状动脉狭窄程度的相关性研究[J].检验医学与临床,2015,(12):1723-1724,2.

检验医学与临床

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1672-9455

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