检验医学与临床Issue(13)：1885-1886,2.DOI:10.3969/j.issn.1672-9455.2015.13.028
莫沙必利与培菲康联合治疗功能性便秘的临床疗效及安全性分析
Analysis on clinical efficacy and safety of mosapride combined with bifico in treatment of functional constipation
方亮 1王昌权 1陈颖 1吴继雄1
作者信息
- 1. 湖北省黄冈市中心医院消化内科 438000
- 折叠
摘要
Abstract
Objective To investigate the clinical safety and efficacy of mosapride combined with bifico in the treatment of functional constipation .Methods 120 cases of functional constipation in our hospital from February 2011 to March 2013 were selected and divided into three group A ,B and C with 40 cases in each group according to the random number table method .The group A was given the combination therapy of mosapride and bifico ,the group B was treated with mosapride and the group C was given with bifico for 5 weeks .The clinical effect and the occur‐rence rate of adverse reactions after stopping drug were analyzed .Results The effective rate in the group A was 90 .00% ,which was higher than 60 .00% in the group B and 47 .50% in the group C (P< 0 .05) ;the relapse rate in the group A was 7 .50% ,which was lower than 37 .50% and 40 .00% in the group B and C (P< 0 .05) ;the occur‐rence rate of adverse reactions was 10 .00% in the group A ,7 .50% in the B group and 7 .50% in the group C ,the difference had no statistical significance (P> 0 .05) .Conclusion Mosapride combined with bifico has a good clinical curative effect in the treatment of functional constipation ,which is safe and reliable with low recurrence rate and is worthy of clinical promotion and application .关键词
莫沙必利/培菲康/功能性便秘/临床疗效/安全性Key words
mosapride/bifico/functional constipation/clinical efficacy/safety引用本文复制引用
方亮,王昌权,陈颖,吴继雄..莫沙必利与培菲康联合治疗功能性便秘的临床疗效及安全性分析[J].检验医学与临床,2015,(13):1885-1886,2.
