摘要
Abstract
Objective To perform the comparative study on the endocrine test results before and after pituitary prolactinomas surgery .Methods The clinical data in 48 cases of pituitary prolactinomas surgery in our hospital from March 2012 to March 2014 were statistically analyzed .Results All patients did not need blood transfusion during surgery .The transsphenoidal microsurgery time via single nostril approach was 1 .0 - 2 .5 h ,average (1 .5 ± 0 .3) h ;transcranial operative time was 1 .6 - 3 .0 h ,average (2 .5 ± 0 .1) h ;the E2 ,LH and P levels on postoperative 1 d ,1 , 3 ,6 months were significantly higher than those before surgery (P< 0 .05) ,serum prolactin(PRL) level was signifi‐cantly lower than that before surgery (P < 0 .05) ;the follicle‐stimulating hormone (FSH ) level at postoperative 1 month was significantly higher than that before surgery (P< 0 .05) ,but the FSH levels had no statistical differences between before surgery and on postoperative 1 d ,3 ,6 months (P> 0 .05) .Conclusion In the treatment of pituitary prolactinomas ,the microsurgery excision of the tumor can effectively improve the endocrine indexes of patients ,is safe and convenient ,and can be used as the main treatment method .Clinic should also detect patients′ preoperative and postoperative endocrine indicators carefully ,then fully use the changes of the detection values ,thus obtain better effect for the treatment of the patients and provide good preconditions for reducing the relapse rate of patients to the lowest .关键词
垂体泌乳素腺瘤/手术前后/内分泌检测结果/对比研究Key words
pituitary prolactinomas/before and after surgery/endocrine test results/comparative study
