检验医学与临床Issue(14)：2011-2013,3.DOI:10.3969/j.issn.1672-9455.2015.14.014
降钙素原在获得性免疫缺陷综合征患者机会性感染早期诊断和疗效观察中的应用
Application of procalcitonin in early diagnosis and curative effect observation of opportunistic infections in AIDS pa-tients
摘要
Abstract
Objective To investigate whether the PCT index can serve as an early diagnostic basis of oppor-tunistic infection in AIDS patients,differentiate bacterial infection from non-bacterial infection in the AIDS patients with opportunistic infections,and its role in the curative effect observation.Methods 1 98 patients with AIDS oppotu-nitic infection were hospitalized,the following detections before the anti-infection treatment were performed:PCT, CRP,WBC count and related pathogens routine tests.Results The positive rate of the routine pathogens detection methods was only 57.6%,whereas which by adopting PCT reached to 90.4%,indicating that PCT had high sensitivi-ty.At the same time by the comparison of PCT,CRP and WBC count among the bacterial infection group,non-bacte-rial infection group,HIV patients group and healthy control group,the results showed that PCT and CRP had statis-tical difference among the bacterial infection group,non-bacterial infection group and healthy control group (P <0.05),while WBC count had no statistical difference(P >0.05);the PCT level had statistical difference between the bacterial infection group and the non-bacterial infection group(P <0.05).Conclusion PCT could be used as the basis for preliminarily judging AIDS oppotunitic infection.关键词
获得性免疫缺陷综合征/降钙素原/C 反应蛋白/白细胞计数Key words
AIDS/PCT/CRP/WBC count引用本文复制引用
石亚玲,何浩岚,黄颖怡,邱玖香,江鸿雅..降钙素原在获得性免疫缺陷综合征患者机会性感染早期诊断和疗效观察中的应用[J].检验医学与临床,2015,(14):2011-2013,3.基金项目
广东省医学科研基金资助项目(A2012515)。 （A2012515）
