口腔颌面外科杂志Issue(4)：249-255,7.DOI:10.3969/j.issn.1005-4979.2014.04.001
肿瘤干细胞与化疗耐药
Cancer Stem Cell and Drug Resistance
摘要
Abstract
Chemotherapy is an indispensable component of systemic therapy on patients with advanced malignancies, yet the outcome is not always success due to the drug resistance of cancer cells. Cancer stem cells are a subpopulation of tumor cells that can initiate tumor formation. If chemotherapy kills bulk of cells within a tumor but not cancer stem cells, the surviving cancer stem cells can initiate the formation of recurrent tumors. This article discusses recent progresses related to cancer stem cell and drug resistance. Approaches to target cancer stem cells to improve the efficacy of chemotherapy will also be discussed.关键词
肿瘤干细胞/耐药/化疗Key words
cancer stem cell/drug resistance/chemotherapymolar/complication分类
医药卫生引用本文复制引用
张萍..肿瘤干细胞与化疗耐药[J].口腔颌面外科杂志,2014,(4):249-255,7.基金项目
国家自然科学基金面上项目（81272978），上海高校特聘教授（东方学者）岗位计划资助 （）
