临床肝胆病杂志Issue(6)：481-484,4.DOI:10.3969/j.issn.1001-5256.2014.06.001
直接抗病毒药物时代下丙型肝炎研究面临的挑战
The challenges to hepatitis C research in era of direct antiviral agents
钟劲 1陶万银1
作者信息
- 1. 中国科学院上海巴斯德研究所，上海200025
- 折叠
摘要
Abstract
Hepatitis C virus (HCV)is an important human pathogen that causes chronic viral hepatitis worldwide.HCV infection,often persistent and asymptomatic,could lead to liver fibrosis/cirrhosis and hepatocellular carcinoma.The interferon/ribavirin therapy has been widely used for treating chronic hepatitis C,but it is not always effective and has strong side effects.The development of small-molecule di-rect antiviral agents (DAA)has greatly improved the curing efficiency of chronic hepatitis C therapeutics and will likely replace the interfer-on-based therapy in the future.However,these developments do not necessarily suggest that the problems of chronic hepatitis C have been completely solved.The HCV research is still facing many challenges in this new DAA era.关键词
丙型肝炎/直接抗病毒药物/综述Key words
hepatitis C/direct antiviral agents/review分类
医药卫生引用本文复制引用
钟劲,陶万银..直接抗病毒药物时代下丙型肝炎研究面临的挑战[J].临床肝胆病杂志,2014,(6):481-484,4.
