临床肝胆病杂志Issue(8)：746-748,3.DOI:10.3969/j.issn.1001-5256.2014.08.012
经内镜鼻胆管引流对接受经内镜逆行胰胆管造影的胆总管结石患者并发术后胰腺炎的预防效果观察
Clinical effect of endoscopic nasobiliary drainage in prevention of post-ERCP pancreatitis in patients with choledo-cholithiasis
赵孝文 1鲍峻峻 2胡翠 1丁浩 1徐张巍 1刘晓昌 1梅俏 1许建明1
作者信息
- 1. 安徽医科大学第一附属医院 消化内科，合肥230000
- 2. 安徽医科大学第一附属医院 腔镜中心，合肥230000
- 折叠
摘要
Abstract
Objective To investigate the clinical effect of endoscopic nasobiliary drainage (ENBD)in the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)pancreatitis (PEP)and hyperamylasemia in patients with choledocholithiasis.Methods A total of 560 patients with choledocholithiasis who underwent ERCP from October 2010 to December 2013 were included in the study.ENBD was performed in 371 patients (test group),and the other 189 patients were designated as control group.Serum amylase level was measured at 3 and 24 h after ERCP,and the incidence of PEP and hyperamylasemia was determined.Comparison of continuous data between the two groups was made by t test,while comparison of rates was made by chi-square test.Results The incidence rates of PEP and hyperamy-lasemia in the test group were 8.1% (30/371)and 13.7% (51/371),respectively,significantly lower than those in the control group (13.8%,26/189;21.2%,40/189),(χ2 =4.47,P=0.034;χ2 =5.06,P=0.024).The serum amylase levels at 3 and 24 h after ERCP in the test group were 215.34 ±304.00 U/L and 199.38 ±273.32 U/L,respectively,significantly lower those in the control group (283.28 ±261.76 U/L and 257.05 ±199.25 U/L)(t=2.61,P=0.01;t=2.57,P=0.01).Conclusion ENBD can effectively re-duce the incidence of PEP and hyperamylasemia in patients with choledocholithiasis.关键词
胆总管结石/胰腺炎/高淀粉酶血症/胰胆管造影术,内窥镜逆行/引流术Key words
choledocholithiasis/pancreatitis/hyperamylasemia/cholangiopancreatography,endoscopic retrograde/drainage分类
医药卫生引用本文复制引用
赵孝文,鲍峻峻,胡翠,丁浩,徐张巍,刘晓昌,梅俏,许建明..经内镜鼻胆管引流对接受经内镜逆行胰胆管造影的胆总管结石患者并发术后胰腺炎的预防效果观察[J].临床肝胆病杂志,2014,(8):746-748,3.
