临床肝胆病杂志Issue(9)：935-938,4.DOI:10.3969/j.issn.1001-5256.2014.09.025
T细胞免疫球蛋白黏蛋白分子3与HBV感染的研究进展
Research progress in TIM-3 and HBV infection
摘要
Abstract
Studies have found that T cell Ig-and mucin-domain-containing molecule-3 (TIM-3)is associated with the development of many diseases.In hepatitis B virus (HBV)infection,TIM-3 acts as a negative immune regulatory molecule and its expression on CD8 +T cells increases markedly.It indicates that TIM-3 is closely related to the pathogenic mechanism of HBV infection.The latest research progress in TIM-3 and HBV infection,including the biological characteristics of TIM-3 and the outcomes and new therapeutic target of HBV infection,is reviewed and summarized.It is thought that TIM-3 will become a new target in the treatment of HBV.关键词
肝炎病毒,乙型/T细胞免疫球蛋白黏蛋白分子3/综述Key words
hepatitis B virus/T cell immunoglobulin and mucin domin containing molecule-3/review分类
医药卫生引用本文复制引用
董杰,申焕君,杨晓菲,赵荣荣,张野,赵燕燕,黄长形,连建奇..T细胞免疫球蛋白黏蛋白分子3与HBV感染的研究进展[J].临床肝胆病杂志,2014,(9):935-938,4.基金项目
国家自然科学基金资助项目 （）
