临床肝胆病杂志Issue(12)：1287-1291,5.DOI:10.3969/j.issn.1001-5256.2014.12.013
腹腔镜肝切除术治疗结肠癌肝转移的系统评价
Clinical effect of laparoscopic hepatectomy in treating liver metastasis of colon cancer:a systematic review and meta-analysis
摘要
Abstract
Objective To evaluate the clinical effects of laparoscopic hepatectomy (LH)versus open hepatectomy (OH)in treating liver metastasis of colon cancer.Methods Relevant literature published up to October 2014 was retrieved from databases including PubMed, Medline,Embase,and Cochrane Library.Extended search was done with reference to the retrieved articles.The quality of selected studies was assessed by the Jadad scale.Meta-analysis was performed using the Cochrane Review Manager software (Version 5.3.4).Results A total of 10 studies involving 786 patients met the inclusion criteria.Meta-analysis showed no significant differences in duration of opera-tion,perioperative mortality,and 5 -year overall survival rate between patients undergoing LH and OH (95%CI:-61.98-23.68,0.08-4.05,and 0.60-1.58,respectively,P>0.05 for all),but there were significant differences in intraoperative blood loss,incidence of post-operative complications,and length of hospital stay (95% CI:-323.17-(-113.00),0.38-0.77,and -5.01 -(-2.04),respec-tively,P<0.05).Conclusion The results of this meta-analysis suggest that LH has comparable efficacy and safety to OH in treating liv-er metastasis of colon cancer and LH has its own advantage.关键词
腹腔镜/肝切除术/结肠肿瘤/肿瘤转移/Meta分析Key words
laparoscopes/hepatectomy/colonic neoplasms/neoplasm metastasis/Meta-analysis分类
医药卫生引用本文复制引用
沈艺南,黄晟宇,胡贤荣,王杰,禹鸿鸣,陆文,卢军华,杨广顺,吴孟超..腹腔镜肝切除术治疗结肠癌肝转移的系统评价[J].临床肝胆病杂志,2014,(12):1287-1291,5.基金项目
国家自然科学基金资助项目 （）
