临床肝胆病杂志Issue(4)：569-572,4.DOI:10.3969/j.issn.1001-5256.2015.04.022
强化营养对原发性肝癌患者行经肝动脉化疗栓塞术治疗效果的影响
Efficacy of nutritional intervention in patients with primary hepatocellular carcinoma treated by transcatheter arterial chemoembolization
摘要
Abstract
Objective To investigate the efficacy of short-term nutritional intervention in patients with primary hepatocellular carcinoma treated by transcatheter arterial chemoembolization.Methods Sixty patients with primary hepatocellular carcinoma who were admitted to Beijing Youan Hospital to receive transcatheter arterial chemoembolization from January 2012 to October 2012 were equally and non-ran-domly divided into two groups:nutrition group and control group.The two groups were all given nutrition guidance after transcatheter arterial chemoembolization.The nutrition group was given 15 g liver essentials twice a day (one in the morning and the other in the evening)by oral administration for 4 weeks,while the control group was given routine diet for 4 weeks.Comparison of data between the two groups was made by independent-samples t test.Results After 4 weeks of continuous treatment,the two groups had significantly increased body weight (P<0.05),arm muscle circumference (P<0.05),and triceps skinfold thickness (P<0.05).The two groups had significantly increased to-tal protein (67 ±13 g/L vs 72 ±9 g/L,P=0.04;66 ±10 g/L vs 74 ±8 g/L,P=0.02)after treatment,and there was a significant differ-ence in changes in total protein after treatment between the two groups (P=0.04).The nutrition group had significantly increased albumin (34.7 ±2.9 g/L vs 39.9 ±3.5 g/L,P=0.03)and cholinesterase (3342 ±415 U/L vs 4600 ±459 U/L,P=0.01)after treatment,and there was a significant difference in changes in albumin (P=0.03)and cholinesterase (P=0.03)after treatment between the two groups. Conclusion For patients with primary hepatocellular carcinoma treated by transcatheter arterial chemoembolization,oral administration of liver essentials improves their nutritional status and liver function,so as to increase their tolerance to subsequent treatments.关键词
肝肿瘤/肠道营养/化学栓塞,治疗性/治疗结果Key words
liver neoplasms/enteral nutrition/chemoembolization,therapeutic/treatment outcome分类
医药卫生引用本文复制引用
扈彩霞,郑加生,崔石昌,钱智玲..强化营养对原发性肝癌患者行经肝动脉化疗栓塞术治疗效果的影响[J].临床肝胆病杂志,2015,(4):569-572,4.基金项目
国家科技支撑计划基金（2012BAI15B08）；国家传染病重大专项；（2012ZX 10002015－002）；佑安肝病艾滋病基金 （）
