临床肝胆病杂志Issue(5)：790-795,6.DOI:10.3969/j.issn.1001-5256.2015.05.040
循环 microRNAs 在肝胆胰肿瘤发生发展中的作用
Clinical value of circulating microRNAs in hepatic,biliary and pancreatic carcinomas
林坤 1次旦旺久 1畅智慧 1刘兆玉1
作者信息
- 1. 中国医科大学附属盛京医院 放射科，沈阳 110004
- 折叠
摘要
Abstract
Recent research demonstrates that microRNA is involved in the growth and development as well as the pathophysiological process of various diseases.In the development and progression of carcinomas,microRNA can function as an oncogene or tumor suppressor depen-ding on the context.Furthermore,the microRNAs corresponding to a specific carcinoma exist in the blood circulation.This study discusses the circulating microRNAs associated with hepatic,biliary and pancreatic carcinomas,which have been recently reported in Chinese and in-ternational studies.The value of microRNA in diagnosis,clinical pathological classification,treatment,and prognosis of hepatic,biliary and pancreatic carcinomas is reviewed.Our study indicates the potential role of circulating microRNA as a novel biomarker for clinical detection, diagnosis,treatment,and prognostic evaluation of carcinomas.关键词
肝肿瘤/胆道肿瘤/胰腺肿瘤/微RNAs/综述Key words
liver neoplasms/biliary tract neoplasms/pancreatic neoplasms/microRNAs/review分类
医药卫生引用本文复制引用
林坤,次旦旺久,畅智慧,刘兆玉..循环 microRNAs 在肝胆胰肿瘤发生发展中的作用[J].临床肝胆病杂志,2015,(5):790-795,6.
