临床骨科杂志Issue(5)：604-607,4.DOI:10.3969/j.issn.1008-0287.2014.05.043
破裂型与未破裂型腰椎间盘突出组织超微结构对比观察
Ruptured and unruptured comparative study of lumbar disc tissue ultrastructure
陶帅 1姜宏 2王铠 1刘锦涛 2戴瑜 1沈绍勇1
作者信息
- 1. 泰州市中医院骨科，江苏 泰州 225300
- 2. 苏州市中医院骨科，江苏 苏州 215009
- 折叠
摘要
Abstract
Objective To compare ruptured and unruptured lumbar disc tissue ultrastructure to determine reabsorption mechanism. Methods 30 cases of patients with lumbar disc herniation surgical specimens, according to intraopera-tive findings were divided into 14 cases of ruptured and unruptured 16 cases. Treatment was made by the norms ultra-thin sections, the use of transmission electron microscopy. Results Ruptured disc low cell density,cell weeks colla-gen fibers shortening,cells were polygonal or similar round organelles metabolically active,“vacuole sign” clearly;un-ruptured disc periplasmic more regular arrangement of collagen fibers,elongated cells spindle-shaped or oval,mem-brane folds, small organelles,cells appeared indications dissolution nucleolus. Conclusions Lumbar disc rupture af-ter the break longitudinal ligament tissue into the epidural space,access to nutritious part of the metabolic pathway re-store gradually abundant cytoplasm,the cell has returned from long fusiform to polygonal or circular,Golgi apparatus, rough endoplasmic reticulum other parts of the cell is activated,“vacuoles” obvious structure;simultaneous immuno-logical autophagy and apoptosis,help to highlight the organization reabsorption.关键词
破裂型/未破裂型/腰椎间盘突出/超微结构Key words
rupture/unruptured/lumbar disc herniation/ultrastructure分类
医药卫生引用本文复制引用
陶帅,姜宏,王铠,刘锦涛,戴瑜,沈绍勇..破裂型与未破裂型腰椎间盘突出组织超微结构对比观察[J].临床骨科杂志,2014,(5):604-607,4.
