林产化学与工业Issue(3)：55-59,5.DOI:10.3969/j.issn.0253-2417.2014.03.010
丙烯海松酸及其噻二唑衍生物的制备及抑菌活性
Synthesis and Antibacterial Activity of Acrylpimaric Acid and Its Thiadiazole Derivatives
摘要
Abstract
Acrylpimaric acid was prepared from rosin through Diels-Alder addition reaction, and then a series of thiadiazole derivatives from acrylpimaric acid were synthesized. Acrylpimaric Acid and its thiadiazole structures were characterized by IR, 1H NMR, MS, and elemental analysis. The antibacterial activities of these newly synthesized derivatives against Gram-negative bacteria and Gram-positive bacteria were also investigated. The results indicated that these compounds displayed extensive anti-bacterial activity against Gram-negative bacteria and gram-positive bacteria. Especially, compound 5f exhibited excellent antibacterial activity against Escherichia coli than bromogeramine. Compared with bromo-geramine (128 mg/L), compound 5f (64 mg/L) possessed a lower MIC value.关键词
松香/丙烯海松酸/噻二唑/抑菌活性Key words
rosin/acrylpimaric acid/thiadiazole/antibacterial activity分类
化学化工引用本文复制引用
李健,饶小平,宋湛谦,肖国民,商士斌..丙烯海松酸及其噻二唑衍生物的制备及抑菌活性[J].林产化学与工业,2014,(3):55-59,5.基金项目
“十二五”国家科技支撑计划资助项目(2012BAD32B03) （2012BAD32B03）
