林产化学与工业Issue(2)：8-16,9.DOI:10.3969/j.issn.0253-2417.2015.02.002
N-（5-去氢枞基-1,3,4-噻二唑-2-基-）-N′-取代基硫脲衍生物的合成及杀虫活性的研究
Synthesis and Insecticidal Activities of N-(5-Dehydroabietyl-1,3,4-thiadiazol-2-yl)-N′-substituted Thioureas
摘要
Abstract
In order to search for biorational pesticides, a series of novel 1,3,4-thiadiazole thiourea derivatives (3a-3k) containing dehydroabietic acid ( DHA) structure were designed and synthesized. Their structures were characterized by IR, MS, NMR, and elemental analysis. The insecticidal activities were investigated against cotton bollworm ( Helicoverpa armigera) , corn borer ( Ostrinia nubilalis ) , and diamondback moth ( Plutella xylostella ) . The preliminary bioassay showed that, at the concentration of 200 mg/L, compounds 3a and 3c exhibited excellent insecticidal activities against H. armigera, with mortality rates of 93. 3% and 83. 3%, respectively, and compounds 3b, 3c, 3d, and 3i displayed moderate insecticidal activities against O. nubilalis with mortality rates of 66. 7%, 66. 7%, 73. 3%, and 60%, respectively. In addition, the structure-insecticidal activity relationship of these compounds was discussed,too.关键词
去氢枞酸/1 ,3 ,4-噻二唑/硫脲/合成/杀虫活性Key words
dehydroabietic acid/1,3,4-thiadiazole/thiourea/synthesis/insecticidal activity分类
化学化工引用本文复制引用
莫启进,刘陆智,段文贵,岑波,林桂汕,陈乃源,黄艳,刘布鸣..N-（5-去氢枞基-1,3,4-噻二唑-2-基-）-N′-取代基硫脲衍生物的合成及杀虫活性的研究[J].林产化学与工业,2015,(2):8-16,9.基金项目
国家自然科学基金资助项目(31060100) （31060100）
广西中药质量标准研究重点实验室基金项目(桂中重开201203) （桂中重开201203）
