林产化学与工业Issue(2)：154-162,9.DOI:10.3969/j.issn.0253-2417.2015.02.024
油橄榄羟基酪醇的生物合成及其衍生物研究进展
Advance in Biosyntheses and Biological Activities of Olive Hydroxytyrosol and Its Derivatives
摘要
Abstract
Chemical syntheses of hydroxytyrosol from different materials were investigated. Its disadvantages included long route, the low yield of product, and expensive catalyst as well as toxic reactants,etc. . This paper emphatically summarized biological synthetic routes for hydroxytyrosol with oleuropein and tyrosol. Furthermore, the syntheses and biological activities of hydroxytyrosol alkyl ether, lipophilic fatty acid ester, and glucoside derivatives, and structure-activity relationship were introduced. It is important to further study the syntheses of hydroxytyrosol and derivatives, and exploit new medicine of anti-tumor, anticancer, cardiovascular and cerebrovascular diseases.关键词
羟基酪醇/羟基酪醇烷基醚/羟基酪醇糖苷/脂肪酸酯/生物转化Key words
hydroxytyrosol/alkyl ether/lipophilic fatty acid ester/glucosylated derivatives/biological transformation分类
化学化工引用本文复制引用
原姣姣,叶建中,王成章,鲁黎..油橄榄羟基酪醇的生物合成及其衍生物研究进展[J].林产化学与工业,2015,(2):154-162,9.基金项目
甘肃省科技重大专项(143NKDK025) （143NKDK025）
国家林业局推广项目(2012-18) （2012-18）
