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Bcl-xL、Livin在牙源性角化囊性瘤组织中的表达及意义

姜颖 陈楠 张铁柱 陈坤 张荣幸

临床口腔医学杂志Issue(6):329-330,331,3.
临床口腔医学杂志Issue(6):329-330,331,3.DOI:10.3969/j.issn.1003-1634.2014.06.004

Bcl-xL、Livin在牙源性角化囊性瘤组织中的表达及意义

Expression of Bcl-xL,Livin in keratocystic odontogenic tumor and the clinical significance

姜颖 1陈楠 1张铁柱 1陈坤 1张荣幸1

作者信息

  • 1. 广东医学院附属医院口腔科 广东 湛江 524001
  • 折叠

摘要

Abstract

Objective:To study the expression of two apoptosis inhibtors:Bcl-xL and Livin in keratocystic odontogenic tumor and the clinical significance. Method:The cases comprised 32 keratocystic odontogenic tumors (KCOT)、30 unicystic ameloblastomas (UA)、30 dentigerous cysts (DC). The expression of Bcl-xL and Livin were evaluated by the immunohisto-chemical techniques. Result:The positive rates for the expression of Bcl-xL in KCOT、UA、DC were 84.38 %、90.00 %、36.67 %.The positive rates for the expression of Livin in KCOT、UA、DC were 59.38 %、66.67 %、20.00 %. Bcl-xL has a positive expressional correlation with Livin in KCOT. Conclusion:Bcl-xL and Livin might be involved in the pathogenesis and progress of KCOT,and possibly cooperate in the biological mechanisms of KCOT.

关键词

牙源性角化囊性瘤/凋亡/Bcl-xL/Livin

Key words

keratocystic odontogenic tumor/apoptosis/Bcl-xL/Livin

分类

医药卫生

引用本文复制引用

姜颖,陈楠,张铁柱,陈坤,张荣幸..Bcl-xL、Livin在牙源性角化囊性瘤组织中的表达及意义[J].临床口腔医学杂志,2014,(6):329-330,331,3.

基金项目

广东省医学科研基金(A2013435)广东医学院附属医院博士科研基金 ()

临床口腔医学杂志

OACSTPCD

1003-1634

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