临床口腔医学杂志Issue(7)：414-416,3.DOI:10.3969/j.issn.1003-1634.2014.07.012
唾腺上皮肌上皮癌伴高级别转化的临床病理观察及文献复习
Epithelial-myoepithelial carcinoma with high-grade transformation:a clinicopathologic study of a case and lit-erature review
陈峰 1杨邵东 1张文峰 1陈新明1
作者信息
- 1. 武汉大学口腔医院 湖北 武汉 430079
- 折叠
摘要
Abstract
Objective:To investigate the clinicopathologic features of epithelial-myoepithelial carcinoma(EMC) with high-grade transformation (HGT). Method:The clinical manifestations,histopathological features and immunohistochemical results of a EMC with HGT were analyzed,with review of the related literatures. Result:The patient was a 60-year-old woman who requested examination of the rapid growth of a mass in the left submandibular area,which he had first noticed 20 years previously. CT revealed an irregular-shaped mass measuring 3.0 cm ×3.4 cm with scattered calcifications in the left submandibular gland. Histologically,the tumor had 2 distinct carcinomatous components,including approximately 80%EMC and 20 % high-grade carcinoma of the whole tumor,respectively. Conclusion:EMC with HGT is extremely rare,and it has more aggressive behavior than typical EMC,with a high propensity for lymph node and distant metastases. The worse progno-sis suggests the need for more radical treatment than in typical low-grade EMC,including wider excision,neck dissection, and possible adjuvant radiation therapy.关键词
唾腺/上皮肌上皮癌/高级别转化/去分化Key words
Salivary gland/Epithelial-myoepithelial carcinoma/High-grade transformation/Dedifferentiation分类
医药卫生引用本文复制引用
陈峰,杨邵东,张文峰,陈新明..唾腺上皮肌上皮癌伴高级别转化的临床病理观察及文献复习[J].临床口腔医学杂志,2014,(7):414-416,3.
