临床口腔医学杂志Issue(10)：610-611,612,3.DOI:10.3969/j.issn.1003-1634.2014.10.011
羟基磷灰石-凝胶支架复合成骨细胞修复兔颅骨缺损的影像学评价
Imaging evaluation of repairing rabbit skull defect with hydroxyapatite/geltin scaffolds
摘要
Abstract
Objective:To investigate the ability of HAP-GEL/osteoblasts scaffolds to repair cranial bone defect. Method:HAP-GEL and osteoblasts were co-culture.The rabbits cranial parietal bone defect models were prepared.Respec-tively HAP-GEL/osteoblasts scaffolds and HAP-GEL scaffolds were implanted into the cranial bone defects area. After 12 weeks,the result was evaluated by gross inspection and imaging evaluation. Result:Blank defects were significantly ridiolu-cent area in the imaging of 12 weeks,HAP-GEL/osteoblasts and HAP-GEL scaffolds were low density area. Conclusion:The engineering bone constructed by HAP-GEL scaffolds and osteoblasts scaffold can be applied to the repair of bone defect in rabbit.关键词
羟基磷灰石/凝胶/成骨细胞/骨缺损/支架材料Key words
hydroxyapatite/geltin/Osteoblasts/Bone defect/Bone scaffold分类
医药卫生引用本文复制引用
耿海霞,Ching-chang Ko,郭秀娟,封伟,吴文..羟基磷灰石-凝胶支架复合成骨细胞修复兔颅骨缺损的影像学评价[J].临床口腔医学杂志,2014,(10):610-611,612,3.基金项目
山东省自然科学基金（ZR2010HL046）；山东省卫生厅科技发展计划项目 （）
