临床神经病学杂志Issue(3)：203-206,4.
重复经颅磁刺激对轻度认知功能障碍患者认知功能的影响
Effects of repetitive transcranial magnetic stimulation on cognitive function in patients with mild cognitive impairmen
章礼勇 1袁良津 1王玉2
作者信息
- 1. 246003安徽医科大学附属安庆医院神经内科
- 2. 安徽医科大学附属第一医院神经内科
- 折叠
摘要
Abstract
Objective To explore the effects of repetitive transcranial magnetic stimulation ( rTMS ) on cognitive function in patients with mild cognitive impairmen ( MCI).Methods Fifty patients with MCI were randomly divided into rTMS treatment group ( rTMS group ) and piracetam treatment group ( control group ) , 25 patients in each group .The stimulated point of rTMS treatment were in the bilateral prefrontal area , for one time a day, continuous treatment for 6 d as a courses in rTMS group patients .Two courses of treatment was interval of 3 weeks, a total of 4 courses.The patients of control group were treated with piracetam 0.8 g, 3 times a day, for taking 16 weeks.Before and after treatment, the event-related potentials P300 and Montreal Cognitive Assessment (MoCA) scale examination were taken in two group respectively .Results Compared with before treatment , the P300 latency significant was significantly shortened and amplitude increased , scores of MoCA scale and delay memory were significantly increased (P<0.05-0.01) after treatment in the rTMS group.Compared with the control group, the difference of those had statistical significance ( all P<0.05 ) .The difference of those had no statistical significance before and after treatment in control group .Conclusion rTMS treatment can improve memory and cognitive in patients with MCI .It can delay the progress of dementia to some extent .关键词
重复经颅磁刺激/轻度认知功能障碍/记忆Key words
repetitive transcranial magnetic stimulation/mild cognitive impairment/memory分类
医药卫生引用本文复制引用
章礼勇,袁良津,王玉..重复经颅磁刺激对轻度认知功能障碍患者认知功能的影响[J].临床神经病学杂志,2014,(3):203-206,4.
