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A型肉毒毒素局部注射治疗面肌痉挛的临床疗效

邢九冬 韩利军 魏礼梅

临床神经病学杂志Issue(3):228-229,2.
临床神经病学杂志Issue(3):228-229,2.

A型肉毒毒素局部注射治疗面肌痉挛的临床疗效

Clinical effects of botulinium toxin A local injection treatment for hemifacial spasm

邢九冬 1韩利军 1魏礼梅1

作者信息

  • 1. 223900南京市第一医院集团泗洪县分金亭医院神经内科
  • 折叠

摘要

Abstract

Objective To investigate the clinical effects of botulinum toxin A ( BTX-A) local injection treatment for hemifacial spasm .Methods Seventeen sites were used to inject BTX-A in 46 patients with hemifacial spasm . Before and after treatment , the grades of facial spasm were evaluated .Clinical efficacy was evaluated based on hemifacial spasm rating 4 weeks after treatment .The recurrence of symptoms in patients given repeated BTX-A injection.Results After BTX-A injection, 15 cases of completely relieved , obviously relieved in 29 cases, partial remission in 2 cases;the efficiency was 95.6%.The onset time was (2.6 ±1.1) d;sustained efficacy was (19.1 ± 2.3)weeks.Injection times was 1 in 5 cases, 2 in 23 cases, 3 in 11 cases and 4 or more in 7 cases.The onset time of repeated injection was(2.61 ±1.03) d, the duration was(19.24 ±2.12) weeks and the efficiency was 100%, They had no significant differences between initial and repeated injection .Six cases occurred local facial mild paralysis, and complete recovery after 2-4 weeks.Conclusion BTX-A local injection for hemifacial spasm is a safe and effective treatment , has no significant adverse reaction;and the effect of repeated injection is not decreased .

关键词

面肌痉挛/A型肉毒毒素/治疗

Key words

hemisfacial spasm/Botulinum toxin A/therapy

分类

医药卫生

引用本文复制引用

邢九冬,韩利军,魏礼梅..A型肉毒毒素局部注射治疗面肌痉挛的临床疗效[J].临床神经病学杂志,2014,(3):228-229,2.

临床神经病学杂志

OA北大核心CSTPCD

1004-1648

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