临床神经病学杂志Issue(3)：221-223,3.
不同时间窗超选择眼动脉溶栓治疗视网膜中央动脉阻塞的疗效观察
Research on effection of different time windows super-selective ophthalmic artery thrombolysis for treatment of central retinal artery occlusion
聂大奥 1谌燕飞 2焦立群 2陈俊抛 1胡欢 1徐基瑛1
作者信息
- 1. 510317 广州，广东省第二人民医院神经内科
- 2. 首都医科大学宣武医院神经介入治疗中心
- 折叠
摘要
Abstract
Objective To observe the effect of different time windows super-selective transcatheter thrombolysis for treatment of central retinal artery occlusion .Methods Twenty-six patients with unilateral central retinal artery occlusion were selected .According to the time from onset to arterial thrombolysis , patients were divided into A group (3 h-72 h,n=16) and B group(72 h-5 d,n=10).Adopting Seldinger technology , microcatheter superselective ophthalmic artery, intravenous infusion of urokinase 250 000-500 000 U(10 000 U/min) for thrombolytic therapy;the curative effects of two groups were compared .Results After thrombolysis the visual improvement rate of A group was significantly better than B group (87.50% VS 70.00%), and the significant efficiency of A group was higher than that of B group (37.50%VS 20.00%);contrast visual acuity improvement rate and improvement rate of retinal artery perfusion, visible each vision improvement rate was higher than the retinal arterial perfusion improvement rate (A group: 87.50% VS 81.25%; B group: 70% VS 50%).Conclusions Superselective ophthalmic artery thrombolysis is a safe , effective treatment of central retinal artery embolism measures .5 d intervention is effective intervention , the effect of early intervention group is better than delayed intervention group , but for the specific patient must follow the principle of individualized treatment .关键词
视网膜中央动脉阻塞/眼动脉溶栓/时间窗/尿激酶Key words
central retinal artery occlusion/ophthalmic artery thrombolysis/time windows/urokinase分类
医药卫生引用本文复制引用
聂大奥,谌燕飞,焦立群,陈俊抛,胡欢,徐基瑛..不同时间窗超选择眼动脉溶栓治疗视网膜中央动脉阻塞的疗效观察[J].临床神经病学杂志,2015,(3):221-223,3.
