临床神经外科杂志Issue(3)：193-196,4.DOI:10.3969/j.issn.1672-7770.2014.03.011
髓母细胞瘤复发、播散性种植及预后的相关因素分析
Analysis on correlation factors of relapse,metastasis and prognosis of medulloblastoma
宋飞 1许百男 1张军1
作者信息
- 1. 100853 北京，解放军总医院神经外科
- 折叠
摘要
Abstract
Objective To discuss the factors that influence the local relapse , implantative metastasis,post operational prognosis of patients suffering from medulloblastoma (MB).Methods The data of 43 patients with MB treated in our department were retrospectively analyzed with Log -Rank test to estimate effects of T stage , extent of resection and radiotherapy on local relapse , implantative metastasis, post operational prognosis .Results The overall three-year,five-year survival rates were 68.3%and 50.1% respectively .The factors that were significantly associated with post operational local recurrences and overall survival time were tumor T stage ,extent of resection and radiotherapy . The differences between tumor T stages ,radiotherapy were significant in implantative metastasis ,while the difference between extents of resection was not .Conclusions Patients with a tumor of T1 or T2 stage and those received post operational craniospinal irradiation have longer recurrence -free time, metastasis-free time and overall survival time .And complete resection can prolong recurrence-free time and overall survival time ,but shows no significant effect on implantative metastasis time .关键词
髓母细胞瘤/治疗/复发/转移/预后Key words
medulloblastoma/treatment/relapse/metastasis/prognosis分类
医药卫生引用本文复制引用
宋飞,许百男,张军..髓母细胞瘤复发、播散性种植及预后的相关因素分析[J].临床神经外科杂志,2014,(3):193-196,4.
