临床误诊误治Issue(10)：88-90,3.DOI:10.3969/j.issn.1002-3429.2014.10.034
泌尿生殖道支原体感染病原体及耐药趋势（附1430例报告）
Infection Situation and Drug Sensitivity Research of Mycoplasma in Urinary and Genital Tract：A Report of 1430 Cases
宋娟 1杜宇 2于颖 1孙婷 1李杨 1李苏利 1张艳1
作者信息
- 1. 071000 河北 保定，解放军252医院检验科
- 2. 071000 河北保定，保定市第二医院放射科
- 折叠
摘要
Abstract
Objective To investigate the infection situation and drug resistance tendency of ureaplasma urealyticum ( Uu) and mycoplasma hominis ( Mh) for improving clinical diagnosis and treatment. Methods During July 2012 and Febru-ary 2014, a total of 1430 patients with suspect urogenital tract infection from Department of Gynaecology and Obstetrics, Uri-nary Surgery and Outpatient Department of Dermatology in our hospital were detected of genitourinary tract secretions for myco-plasma cultivation, and sensitivity test was done to 9 antibacterial drugs, such as doxycycline, minocycline, josamycin, clar-ithromycin, roxithromycin, azithromycin, ofloxacin, levofloxacin, and sparfloxacin. Results There were 788 cases (55. 10%, 788/1430) of mycoplasma infection, and patients aged from 20-40 years accounted for 86. 55% (682/788). The positive rate in female patients was higher than that in male patients (61. 21% vs. 27. 24%,χ2 =98. 35, P<0. 01). There were 578 cases (40. 42%) of Uu infection, 10 cases (0. 70%) of Mh infection, and 200 cases (13. 99%) of mixed infection of Uu and Mh. Mycoplasma showed highest sensitivity to doxycycline (92. 01%) and minocycline (92. 89%), and showed lowest sensitivity to roxithromycin (8. 76%) and ofloxacin (6. 35%). The drug resistance rate showed significant difference between patients with Uu and Mh mixed infection and patients with single Uu infection (P<0. 01). Conclusion Mycoplasma infection rate is on rise and dug resistant strains increase gradually. Clinicians should pay attention to analysis of mycoplasma culture and drug sensitivity test, dynamically monitoring the drug resistance for rational use of antimicrobial agents and reduc-ing the spread of multi-drug resistant strains.关键词
解脲支原体/人型支原体/同时感染/抗菌药/微生物敏感性试验Key words
Ureaplasma urealyticum/Mycoplasma hominis/Coinfection/Anti-bacterial agents/Microbial sensitivity tests分类
医药卫生引用本文复制引用
宋娟,杜宇,于颖,孙婷,李杨,李苏利,张艳..泌尿生殖道支原体感染病原体及耐药趋势（附1430例报告）[J].临床误诊误治,2014,(10):88-90,3.
