临床误诊误治Issue(1)：45-48,4.DOI:10.3969/j.issn.1002-3429.2015.01.014
恶性胸膜间皮瘤误诊为结核性胸膜炎原因分析
Cause Analysis of Malignant Pleural Mesothelioma Misdiagnosed as Tuberculous Pleurisy
摘要
Abstract
Objective To analyze clinical features and diagnosis of malignant pleural mesothelioma, so as to reduce misdiagnosis rate. Methods Clinical data were retrospectively analyzed from one case of malignant pleural mesothelioma in our hospital, and related literature was reviewed. Results Before admission, the patient complained of cough, chest tight-ness and chest pain for one month outside the hospital, and chest CT examination showed left pleural effusion, and the patient received anti TB diagnostic therapy for 2 weeks after examination of pleural effusion, but his symptoms gradually deteriorated, and so he was transferred to our hospital. CT ultrasound examination showed left pleural effusions. The serum neuron specific enolase was as high as 48 ng/ml. Biopsy pathology through thoracoscopy and immunohistochemical confirmed of malignant pleural mesothelioma. After chemotherapy of pemetrexed disodium combined with cisplatin, his symptoms were relieved re-markably and he was discharged from hospital, but his condition deteriorated and died 11 months after discharge. Conclusion When pleural effusion is difficult to characterize, especially with chest pain, malignant pleural mesothelioma should be sus-pected and thoracoscopy and open-chest examination have an important role in definite diagnosis.关键词
胸膜肿瘤/间皮瘤/误诊/结核,胸膜Key words
Pleural tumor/Mesothelioma/Misdiagnosis/Tuberculosis, pleural分类
医药卫生引用本文复制引用
梅周芳,钱凌,都勇,施劲东,何炜,李小静,揭志军..恶性胸膜间皮瘤误诊为结核性胸膜炎原因分析[J].临床误诊误治,2015,(1):45-48,4.基金项目
复旦大学附属上海市第五人民医院曙光青年科研基金(2013YSGQN02) （2013YSGQN02）
