临床小儿外科杂志Issue(2)：99-102,4.DOI:10.3969/j.issn.1671-6353.2014.02.004
累及第二、三肝门巨大肝母细胞瘤手术切除41例
Surgical resection of huge hepatoblastoma involving the second and third hepatic hilums
乔国梁 1李龙 1葛军涛 1刘树立 1张军 1王琛 1张震 1魏延栋1
作者信息
- 1. 首都儿科研究所小儿外科 北京市，100020
- 折叠
摘要
Abstract
Objetive To investigate the feasibility and surgical procedure for huge hepatoblastoma invol-ving the second and third hepatic hilums. In order to expand the indications for hepatectomy,improve treatment of children with hepatoblastoma. Methods 41 patients with huge hepatoblastoma involving the second and third hepatic hilums were evaluated.The patients’age ranged from 3 month to 1 4 years with a mean of 3.8 years.The tumors’diameter ranged from 8.5 ~21.6 cm with a mean of 1 3.5 cm. Kaplan-Meier survival analy-sis was applied to evaluate the survival rates of patients with hepatoblastoma. Results Of the 41 patients who underwent hepatectomy,there was no operative mortality or morbidity.The mean duration of the operations was 220 minutes and the mean blood loss was 1 1 5 mL.The mean time of intermittent portal triad clamping was 22 min. Of the 41 patients,the 1-,3-,5-year even-free survival rate were 92.7%,72.8% and 33.5%,re-spectively. All patients underwent postoperatively regular chemotherapy,20 patients(48.8%)found tumor re-currence after hepatectomy. 5 patients suffered tumor metastases in lung and 3 of them died from that in one year. Conclusion Resecting huge hepatoblastoma involving the main hepatic veins and the retrohepatic vena cava is feasible and safe with accurate preoperative assessment and skillful mastery of the anatomy of the liver.Complete resection of this kind of tumors would effectively improve the long-term survival of hepatoblastoma.关键词
肝肿瘤/肝切除术/预后Key words
Liver Neoplasms/Hepatectomy/Prognosis引用本文复制引用
乔国梁,李龙,葛军涛,刘树立,张军,王琛,张震,魏延栋..累及第二、三肝门巨大肝母细胞瘤手术切除41例[J].临床小儿外科杂志,2014,(2):99-102,4.
