摘要
Abstract
Objetive Glomerular filtration rate (GFR)is an important criterion to evaluate renal func-tion.The aim of this study was to measure and calibrate GFR reference intervals for Chinese children by means of 99mTc-DTPA renal dynamic imaging. Methods 99 children(aged 8weeks~12 years)with normal renal function underwent99m Tc-DTPA renal dynamic imaging to measure GFR using Gate’s method,and was per-formed to measure directly the kidney depth of each case by lateral static scan.The Corrected GFR (cGFR) was obtained from the method.All the cases were divided into five groups by age. Results ①According to the method reported,the GFR were as follows:8weeks~1years,GFR 70 ±10 mL/min,cGFR 84 ±10 mL/min;1 ~2 years,GFR 79 ±6 mL/min,cGFR 94 ±7 mL/min;2 ~3 years,GFR 85 ±5 mL/min,cGFR 98 ±4 mL/min;3~10 years,GFR 84 ±6 mL/min,cGFR 102 ±6 mL/min;10~12 years,GFR86 ±7 mL/min,cGFR 105 ±6 mL/min.②There were significantly difference between GFR and cGFR in our every group (P <0.05 ).The cGFR and eGFR have no sense in statistics in the older children group.③According to the method reported with Gate’s method,the normal reference intervals of GFR were as follows:8 weeks~1 years,GFR 50~90 mL/min,cGFR 60~104 mL/min;1 ~2 years,GFR 67 ~91 mL/min,cGFR 80~108 mL/min;2~3 years,GFR 75 ~95 mL/min,cGFR 90 ~106 mL/min;3 ~10 years,GFR 72 ~96 mL/min,cGFR 90 ~1 14 mL/min;10~12 years,GFR 72~100 mL/min.cGFR 93 ~1 17 mL/min. Conclusion The data provided in this study is of value for evaluating the renal function of Chinese children objectively and quantitatively.关键词
肾/放射性核素显像/肾小球滤过率/研究/儿童Key words
Kidney/RI/Glomerular Filtration Rate/Research/Child
