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中国人近视与原发性开角型青光眼相关性的 Meta 分析

项勇刚 夏凌云 张勇 曾宪涛 许玲

临床眼科杂志Issue(3):259-262,4.
临床眼科杂志Issue(3):259-262,4.DOI:10.3969/j.issn.1006-8422.2014.03.024

中国人近视与原发性开角型青光眼相关性的 Meta 分析

Meta-analysis of association between myopia and primary open angle glaucoma

项勇刚 1夏凌云 2张勇 1曾宪涛 3许玲1

作者信息

  • 1. 442000 湖北十堰,湖北医药学院附属太和医院眼科
  • 2. 442000 湖北十堰,湖北医药学院附属太和医院口腔科
  • 3. 442000 湖北十堰,湖北医药学院附属太和医院循证医学中心
  • 折叠

摘要

Abstract

Objective To explore the association between myopia and primary open angle glaucoma ( POAG) by Meta-analysis.Methods Relevant studies, published up to July 20, 2013, were searched from CNKI and VIP databases . After data extraction, a meta-analysis was performed using CMA (comprehensive meta analysis) v2.2 software.Results Five studies were finally recruited , including 3 studies that reported the association between myopia and POAG independ-ently.The results of meta-analysis showed that myopia evidently increases the risk of POAG by 3.07 times ( OR=3.07, 95%CI=1.90~4.96), and high myopia obviously increases the risk of POAG by 7.15 times (OR=7.15, 95% CI=4.01~12.75).Sensitivity analysis showed that the results were robust .The publication bias analysis was not conducted . Conclusion Based on the current evidence , myopia is probably an independent and significant risk factor for POAG , and the high myopia persons were with higher risk for POAG .

关键词

近视/原发型开角型青光眼/危险因素/Meta分析

Key words

Myopia/Primary open-angle glaucoma/Risk factors/Meta analysis

引用本文复制引用

项勇刚,夏凌云,张勇,曾宪涛,许玲..中国人近视与原发性开角型青光眼相关性的 Meta 分析[J].临床眼科杂志,2014,(3):259-262,4.

临床眼科杂志

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1006-8422

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