临床眼科杂志Issue(5)：397-399,3.DOI:10.3969/j.issn.1006-8422.2014.05.005
儿童视网膜色素变性临床特点分析
Clinical characteristicsof retinitis pigmentosa in children
叶辉 1夏小平1
作者信息
- 1. 510630 广州，中山大学附属第三医院眼科
- 折叠
摘要
Abstract
Objective To investigate the clinical presentation and therapeuticalmethodsof retinitis pigmentosa (RP) in children.Methods Twenty seven children younger than 14 years old who were diagnosed with RP and met the study criteria were enrolled .Patients received Humphrey automatic perimeter examination and were assigned into 2 groups according to the hereditary pattern of the RP (hereditary or non-hereditary).All patients received treatments with docosa-hexaenoic acid, vitamin A palmitate, zeaxanthin, monacolin K and selenium for one year .Visual acuity (VS) and mean deviation ( MD) of visual field were recorded in the beginning and at the end of study .Results The chief complaint of RP were impaired nocturnal vision , and mainly were reported by parents rather than patients themselves .Some asymptomatic patients were brought to clinic because of family history .After one year treatment , mean deficits in perimetry increased in non-hereditary patients ( P <0.05) while were not changed in hereditary patients .There was no change in central visual acuity in both groups .Conclusion Symptoms of RP, e.g., impaired nocturnal vision , were oftennoticed by parents or siblings rather than patients themselves .Automatic perimeter examination is a preferred screening method for RP .Dspite that, mis-diagnosis could still happen to some patients .Treatment outcomeswere generally better in non-hereditary patients than in hereditary patients .关键词
视网膜色素变性/儿童/临床特点Key words
Retinitis pigmentosa/Children/Clinical characteristic引用本文复制引用
叶辉,夏小平..儿童视网膜色素变性临床特点分析[J].临床眼科杂志,2014,(5):397-399,3.
