摘要
Abstract
Objective To observation the short-term effects of Lucentis intravitreal injection on macular edema due to central retinal vein occlusion (CRVO).Methods Twenty-two eyes of 22 patients with macular edema due to CRVO were treated in our hospital .Patients received intravitreal injection of 0.05 ml Lucentis, and were followed with best-cor-rected visual acuity ( BCVA) , fluorescein angiography and central macular thickness ( CMT; by optical coherence tomo-graphy) for at least 4 months.A second intravitreal injection was given when macular edema recurred during the follow -up period.Results The mean follow up was 6.3 ±2.54 months.Before treatment the baseline BCVA ( logMAR) and CMT were 0.66 ±0.52 and 689 ±175? m, respectively.After treatment, mean BVCA significantly improved at 1 week (0.52 ±0.46), 1 month (0.48 ±0.46), 2 months (0.56 ±0.43), and 4 months (0.51 ±0.47).Mean CMT also decreased at 1 week (290 ±86? m, P <0.01), 1 month (280 ±80? m, P <0.01), 2 months (450 ±240? m, P <0.01), and 4 months (362 ±190? m, P <0.01), paralleled with the improvement of BCVA .Conclusion Intravitreal injection of Lu-centis improves visual acuity and macular edema caused by CRVO .关键词
视网膜中央静脉阻塞/黄斑水肿/雷珠单抗Key words
Central retinal vein occlusion/Macular edema/Lucentis/Intravitreal injection
