临床与实验病理学杂志Issue(9)：1026-1029,4.DOI:10.13315/j.cnki.cjcep.2014.09.019
骨外黏液样软骨肉瘤5例并文献复习
Extraskeletal myxoid chondrosarcoma:report of 5 cases and review of literatures
黄文勇 1徐晓 1胡佳莉 1李海 2范钦和2
作者信息
- 1. 九江学院附属医院病理科，九江 332000
- 2. 南京医科大学第一附属医院病理科，南京 210029
- 折叠
摘要
Abstract
Purpose To explore the clinicopathologic characteristics, pathologic diagnosis and differential diagnosis of extraskeletal myxiod chondrosarcoma. Methods The clinical and pathological features were studied with HE and immunohistochemical staining in 5 cases of extraskeletal myxoid chondrosarcoma, and the related literatures were also reviewed. Results Extraskeletal myxoid chondro-sarcoma was male predominance (4 males: 1 female), and the age ranged from 32 to 62 years with an average of 52 years. Four tumors occurred in thigh and another in chest. Histologically, the neophlasm were composed of round and oval cells. Immunohisto-chemically, the tumor cells were positive for vimentin in five cases, synaptophysin expressed in one case, S-100 showed focal positivity in two cases, but negative for CK, p63, EMA, CD34, SMA in all cases. Molecular genetics detection shows chromosome exchange be-tween number 9 and 22. Conclusion Extraskeletal myxoid chondrosarcoma is a rare tumor which has no special characteristics in clinical and iconography, and its diagnosis mainly depends on the histopathologic features, immunohistochemistry and molecular genet-ics. Extraskeletal myxoid chondrosarcoma grows slowly, but have a high tendency for local recurrence and metastases.关键词
骨外黏液样软骨肉瘤/临床病理特征/免疫组织化学Key words
extraskeletal myxoid chondrosarcoma/clinicopathologic characteristics/immunohistochemistry分类
医药卫生引用本文复制引用
黄文勇,徐晓,胡佳莉,李海,范钦和..骨外黏液样软骨肉瘤5例并文献复习[J].临床与实验病理学杂志,2014,(9):1026-1029,4.
