临床与实验病理学杂志Issue(9)：1030-1033,4.DOI:10.13315/j.cnki.cjcep.2014.09.020
甲状腺透明变梁状肿瘤6例临床病理分析
Hyalinizing trabecular tumours of thyroid:a clinicopathologial analysis of 6 cases
刘丽燕 1张声 2刘永建 3陈虹 2蔡世捷 1林晓芸 1陈玉梅1
作者信息
- 1. 福建卫生职业技术学院附属医院福建省级机关医院病理科，福州 350003
- 2. 福建医科大学附属第一医院病理科，福州 350005
- 3. 河北医科大学第一医院体检部，石家庄 050000
- 折叠
摘要
Abstract
Purpose To explore the clinical pathological features and differential diagnoses and therapeutics of hyalinizing trabecular tumours ( HTT) of thyroid. Methods The clinical manifestations, high-frequency color doppler ultrasonography, histopathological and immunohistochemical features were analysed in six cases of HTT of thyroid. Related literatures were reviewed. Results On his-topathological examination, polygonal and elongated cells arranged in pattern of trabecular and organoid, with a clear perinucleolus ha-lo. Basement membrane-like material deposited intertrabeculae widespreadly. The tumour cells are completely filled with eosinophilic and granular material in their cytoplasm, nuclei with prominent grooves and pseudoinclusions. Immunohistochemically, the tumour cells were positive for TG, TTF-1 and CD56, CK19 and Galectin-3 interspersed expression. And all of them were negative for Calcito-nin, MC, CEA, Syn, CgA, Ki-67, p53 were lower expression. The differential diagnosis included solid variant of papillary carcinoma, medullary thyroid carcinoma and paraganglioma and so on. Conclusion HTT is an uncommon thyroid tumor, the majority of them be-have as benign neiplasms and that, correct pathologic diagnosis may play an important role in standard treatment and prognostic evalua-tion of HTT.关键词
甲状腺肿瘤/透明变梁状肿瘤/病理诊断/鉴别诊断/免疫组织化学Key words
thyroid neoplasm/hyalinizing trabecular tumour/pathologic diagnosis/differential diagnosis/immunohistochemistry分类
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刘丽燕,张声,刘永建,陈虹,蔡世捷,林晓芸,陈玉梅..甲状腺透明变梁状肿瘤6例临床病理分析[J].临床与实验病理学杂志,2014,(9):1030-1033,4.
