临床与实验病理学杂志Issue(12)：1398-1402,5.DOI:10.13315/j.cnki.cjcep.2014.12.018
腮腺非皮脂腺淋巴腺瘤2例并文献复习
Nonsebaceous lymphadenoma of salivary gland:report of two cases and review of the litera-ture
吴琼 1李皖云 1武世伍 1周蕾 1欧玉荣1
作者信息
- 1. 蚌埠医学院第一附属医院病理科，蚌埠 233004
- 折叠
摘要
Abstract
Purpose To investigate clinicopathological features, diagnosis and differential diagnosis of non-sebaceous lymphadenoma of the parotid gland. Methods The histopathological morphology, immunohistochemical profiles and clinicopathological features were an-alyzed in two cases of NSL, along with review the related literatures. Results Two patients were female adults. Microscopically, The tumor was a well-circumscribed mass surrounded by a fibrous capsule of variable thickness and comprised a mixture of proliferating epi-thelium accompanied by a prominent lymphoid component, reactive lymphoid follicles were found in lymphoid stroma. The epithelial component took the form of anastomosing trabeculae, glands, solid basaloid islands or cyst formation. The cysts and glands were lined with luminal cells and abluminal cells, filled with eosinophilic secretions with occasional histiocytes. The epithelial cell was no seba-ceous differentiation, significant cytological atypia and mitotic activity. A fibrous capsule with subcapsular sinus was seen around the mass in one case. Immunohistochemically, the abluminal cells were positive for p63, CK34βE12 and CK5/6, while the epithelial cells were positive for CK(AE1/AE3) and CK7. Conclusion NSL is a very rare benign of salivary gland, which occuring in the lymph node lesions are less reported, knowledge of the wide histological spectrum of this rare tumor is important in order to avoid misdiagno-sis, particularly as malignant tumor.关键词
腮腺肿瘤/非皮脂腺淋巴腺瘤/淋巴结/鉴别诊断Key words
parotid gland neoplasms/nonsebaceous lymphadenoma/lymph node/differential diagnoses分类
医药卫生引用本文复制引用
吴琼,李皖云,武世伍,周蕾,欧玉荣..腮腺非皮脂腺淋巴腺瘤2例并文献复习[J].临床与实验病理学杂志,2014,(12):1398-1402,5.
