临床与实验病理学杂志Issue(7)：769-772,4.DOI:10.13315/j.cnki.cjcep.2015.07.012
骨原发性平滑肌肉瘤5例临床病理特征
Clinicopathological features of primary leiomyosarcoma of bone:a report of 5 cases
李梅 1李传应 1刘劲松 2李娟 2李殿炜2
作者信息
- 1. 安徽省六安市人民医院病理科 237005
- 2. 安徽省立医院病理科，合肥 230001
- 折叠
摘要
Abstract
Purpose To explore the clinicopathological features, diagnosis and differential diagnosis of primary leiomyosarcoma of bone and to study its therapy and prognosis. Methods Histopathologic features, immunohistochemical stains and iconography of five cases were analyzed and the related literatures were reviewed. Results The patients consisted of two males and three females with ages ran-ging from 46 to 72 years, who average 58 years. Clinically, most cases presented as pain reaction, of which two cases were located a-round the knee joint, one case was in the upper femur, one case was in the sacrum and another was in the upper jaw. Microscopically, tumor cells were composed of spindle shaped cells, with some epitheloid variants. Immunohistochemically, all the tumor cells were pos-itive for smooth muscle actin and vimentin, and the expression of desmin was found in two cases. But S-100 protein, MyoD1 and CD68 were negative. Conclusions Primary leiomyosarcoma of bone is relatively rare, and clinical symptoms and imaging findings are not specific. The diagnosis depends on immunohistochemistry and electron microscopy.关键词
骨平滑肌肉瘤/临床病理/影像学诊断/免疫组织化学Key words
leiomyosarcoma of the bone/clinicopathology/imaging diagnosis/immunohistochemistry分类
医药卫生引用本文复制引用
李梅,李传应,刘劲松,李娟,李殿炜..骨原发性平滑肌肉瘤5例临床病理特征[J].临床与实验病理学杂志,2015,(7):769-772,4.
