临床与实验病理学杂志Issue(7)：773-775,776,4.DOI:10.13315/j.cnki.cjcep.2015.07.013
骨转移性小细胞癌11例穿刺病理的鉴别诊断
Differentail diagnosis of metastatic small cell carcinoma of bone in needle biopsy:an analysis of 11 cases
田萌萌 1孙晓淇 1张铭 1赵蕾 1孟淑琴1
作者信息
摘要
Abstract
Purpose To investigate the diagnosis and differentail diagnosis of metastatic small cell carcinoma of bone in needle biopsy, especially for the differentail diagnosis with Ewing sarcoma of bone. Methods Clinicopathological informations of 11 cases of metastat-ic small cell carcinoma and 20 cases of Ewing sarcoma were collected, and markers for differentail diagnosis were detected in two groups by immunohistochemistry of EnVision. Results The positive rates of CD99 and FLI-1 were 27. 3% and 54. 5% in metastatic small cell carcinoma group, while the positive rate of CK was 15. 0% in Ewing sarcoma group. Patient′s age, single lesion, expression of CK, vimentin, CD99, FLI-1, CD56 were significantly different in two groups. Conclusions Metastatic small cell carcinoma and E-wing sarcoma share similar histopathologic features in needle biopsy, no single immunohistochemical marker can specifically distinguish small cell carcinoma from Ewing sarcouma. The correct diagnosis should comprehensive analyze clinicopathologic characters and a se-ries of immunohistochemical markers.关键词
小细胞肿瘤/骨转移/Ewing肉瘤/鉴别诊断/免疫组织化学Key words
small cell neoplasm/osseous metastasis/Ewing sarcoma/differentail diagnosis/immunohistochemistry分类
医药卫生引用本文复制引用
田萌萌,孙晓淇,张铭,赵蕾,孟淑琴..骨转移性小细胞癌11例穿刺病理的鉴别诊断[J].临床与实验病理学杂志,2015,(7):773-775,776,4.
