中国临床保健杂志Issue(5)：475-477,3.DOI:10.3969/J.issn.1672-6790.2014.05.010
合肥地区轻度认知功能障碍的流行病学调查及叶酸的干预效果
The epidemiology of mild cognitive impairment and intervention effect of folic acid in Hefei
摘要
Abstract
Objective To investigate the prevalence of mild cognitive impairment (MCI)in hefei,and ob-serve the intervention effect of folic acid for MCI .Method Six hundreds and seventy nine patients were selected from multiple hospital according MMSE and the level of homocysteine.On the basis of MMSE scores,the patients were divided into normal group(A),MCI group(B)and dementia group(C).The MCI group was divided into the treatment group(B1 )and non -treatment group(B2).The MMSE value and Hcy levels were follow -up three years. Results Six hundreds and seventy nine elderly people were surveyed,including 560 normal elderly,92 MCI and 27 dementia patients.Forty -seven new cases of MCI were detected in group A .Ten and sixteen new cases of dementia were developed from MCI in B1 and B2 group.The 36.36% MCI patients were developed into dementia in control group,and 20.83% MCI patients were developed into dementia in intervention group after 3 years.Conclusion The prevalence of MCI and dementia are higher in Hefei elderly.The supplementation of folic acid can retard the pro-gress of MCI.关键词
轻度认知障碍/患病率/半胱氨酸/叶酸Key words
Mild cognitive impairment/Morbidity/Cysteine/Folic acid分类
医药卫生引用本文复制引用
顾辨辨,严光,周树生..合肥地区轻度认知功能障碍的流行病学调查及叶酸的干预效果[J].中国临床保健杂志,2014,(5):475-477,3.基金项目
安徽省国际科技合作计划项目 （）
