皮肤性病诊疗学杂志Issue(5):383-386,4.DOI:10.3969/j.issn.1674-8468.2014.05.008
泛发性脓疱型银屑病28例治疗分析
Analysis of Treatment Outcome in 28 Cases with Generalized Pustular Psoriasis
曾碧冰 1陈明春 2王鲁梅 1李俊杰 1张静 1石宏英 1黎凤娟 1卢婉娇1
作者信息
- 1. 东莞市人民医院皮肤科,广东 东莞 523000
- 2. 中山大学附属第二医院皮肤科,广东 广州510120
- 折叠
摘要
Abstract
Objective:To investigate the pathogenesis , the clinical manifestation , and the treatment of generalized pustular psoriasis ( GPP ) .Methods:The clinical data and treatment process of 28 patients with GPP were retrospective analysed .Results:Many factors could lead to GPP.Infection and irregular use of corticosteroids were the main factors inducing and aggravating GPP.Fever was the common and distinctive systemic symptoms .The elevation in white blood cell counts and ESR were the main laboratory manifestations .The regiments of second generation retin-oic acid ( acitretin ) , immunosuppressant ( methotrexate , MTX ) , acitretin combined with glu-cocorticoid, MTX combined with glucocorticoid had good therapeutic effect on GPP .Conclusion:All of four therapy regiments had good therapeutic effect on GPP .The therapy program should be applied based on the severity of disease , drug effecacy , side effects and tolerance .关键词
泛发性脓疱型银屑病/治疗Key words
Generalized pustular psoriasis/Treatment分类
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曾碧冰,陈明春,王鲁梅,李俊杰,张静,石宏英,黎凤娟,卢婉娇..泛发性脓疱型银屑病28例治疗分析[J].皮肤性病诊疗学杂志,2014,(5):383-386,4.