河南科技大学学报（医学版）Issue(3)：167-169,3.
肾透明细胞癌中KISS-1、VEGF的表达及其临床意义
KISS-1 and VEGF Expression in Renal Clear Cell Carcinoma and Its Clinical Significance
摘要
Abstract
Objective ToinvestigatetheexpressionsandsignificancesofKISS-1andVEGFinrenal clearcellcarcinomatissuesanditsclinicalsignificance.Methods Immunohistochemicaldetectionof31 cases of renal clear cell carcinoma and 15 patients with normal kidney tissue and protein KISS-1 and VEGF expression.Results InrenalclearcellcarcinomaandexpressionofKISS-1proteininrenaltissuesof normal positive rate were 29% and 60%,a statistically significant difference(P<0.05);in renal clear cell carcinoma and normal kidney tissue VEGF expression in 80.6% and 46.7%,respectively,a statistically significant difference(P<0.05 );low undifferentiated,Ⅲ ~Ⅳ and lymph node metastasis in human renal clear cell carcinoma of the KISS-1 expression of differentiation than high schools,respectively,secondary and no lymph node metastasis of Ⅰ~Ⅱ low and undifferentiated,phase Ⅲ ~Ⅳ renal clear cell carcinoma and lymph node metastasis in the differentiation of VEGF expression level than high schools,respectively, secondary and no lymph node metastasis of I ~high. And both expressions are a significant negative correlation(r=-5.086,P<0.05).Conclusion abnormalexpressionofKISS-1protein,VEGFmaybe associated with renal clear cell carcinoma and closely related to invasion and metastasis.关键词
KISS-1/VEGF/肾透明细胞癌/蛋白表达Key words
KISS-1/VEGF/Clear cell renal cell carcinoma分类
医药卫生引用本文复制引用
袁帅,潘梦音,冯凯祥,景东帅,谢明红,李世朋,韩洪波..肾透明细胞癌中KISS-1、VEGF的表达及其临床意义[J].河南科技大学学报（医学版）,2014,(3):167-169,3.基金项目
河南科技大学大学生训练计划（SRTP）项目 （）
