河南科技大学学报（医学版）Issue(2)：93-96,4.
信必可都保联合阿托伐他汀钙对慢性阻塞性肺疾病急性加重期患者炎症因子、肺功能的影响
Effect of Symbicort Turbuhaler Combined with Atorvastatin Calcium on Inflammatory Factors and Lung Function in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective To observe the effect of Symbicort Turbuhaler combined with Atorvastatin calcium in inflammatory factors and lung function in the patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods 100 patients with AECOPD were randomly divided into the control group (50 cases),which were given the basis of conventional therapy and Atorvastatin calcium.The study group(50 cases),which were given Symbicort Turbuhaler on the basis of the control group.The two groups were observed the chang the serum IL-13,CRP and lung function after treatment for 14 days. Results There was no difference in inflammatory factors and lung function in the two groups before treatment (P >0.05).The expressions of CRP、IL-13 were decreased significantly in the study group than the control group after treatment for 14 days(P <0.05),FVC,PEF,FEV1,FEV1 /FVC were increased significantly(P <0.05), the clinical efficacy of the study group were better than control group(P <0.05 ). Conclusion Symbicort Turbuhaler combined with Atorvastatin calcium could significantly improve the lung function,decrease the level of inflammatory in the patients with acute exacerbation of chronic obstructive pulmonary disease.关键词
信必可都保/阿托伐他汀钙/慢性阻塞性肺疾病急性加重期/炎症因子/肺功能Key words
Symbicort Turbuhaler/Atorvastatin calcium/acute exacerbation of chronic obstructive pulmonary disease/inflammatory factors/lung function分类
医药卫生引用本文复制引用
付晓丽,张会凯,赵红军..信必可都保联合阿托伐他汀钙对慢性阻塞性肺疾病急性加重期患者炎症因子、肺功能的影响[J].河南科技大学学报（医学版）,2015,(2):93-96,4.基金项目
河北省科学技术研究与发展计划资金支持项目 （）
