国际眼科杂志Issue(7)：1350-1351,2.DOI:10.3980/j.issn.1672-5123.2014.07.53
A型肉毒毒素治疗眼睑痉挛的临床研究
Clinical study on botulinum toxin A injections for blepharospasm
焦永红 1王乙迪 1潘哲1
作者信息
- 1. 100730 中国北京市，首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科学与视觉科学重点实验室
- 折叠
摘要
Abstract
AlM:To observe the efficacy of using botulinum toxin A in the treatment of blepharospasm. <br> METHODS: Totally 113 patients with blepharospasm were managed with a local injection of botulinum toxin A, and the therapeutic effect was evaluated. <br> RESULTS:Fifty-nine cases ( 52. 2%) had a complete remission of symptoms, 49 patients ( 43. 4%) presented with obvious relieved spasm, 4 cases ( 3. 5%) were partially relieved and the 1 patient ( 0. 9%) remained unchanged. The total effective rate was 99. 1%. The time of beginning effect was 1-14d. The recover time was mostly in 14d. The average of therapeutic effect lasted 1-9mo. Adverse reactions such as mild palpebra dysraphism, palpebra ptosis and local subcutaneous blood stasis were found in 23 patients, and the symptoms disappeared in 2-4wk. <br> CONCLUSlON:Botulinum toxin A can effectively control medium and severe blepharospasm by injecting a little dose on local muscle.关键词
A型肉毒毒素/局部注射/眼睑痉挛Key words
botulinum toxin A/local injection/blepharospasm引用本文复制引用
焦永红,王乙迪,潘哲..A型肉毒毒素治疗眼睑痉挛的临床研究[J].国际眼科杂志,2014,(7):1350-1351,2.
