国际眼科杂志Issue(11)：1995-1998,4.DOI:10.3980/j.issn.1672-5123.2014.11.21
MicroRNAs在视网膜母细胞瘤的研究新进展
New research progress of microRNAs in retinoblastoma
摘要
Abstract
Retinoblastoma(RB)is the most common intraocular malignancy of children with extremely poor prognosis. MicroRNAs are small non-coding single-stranded RNAs in eukaryotic cells, which regulate the expression of gene by mRNA degradation or translation inhibition. MicroRNAs, acting as oncogenes or tumor suppressor genes, are associated with the occurrence and development of RB directly, which is vital for the early diagnosis and clinical targeted therapy of RB. This review summarized the expression of microRNAs in RB and the related mechanism.关键词
microRNAs/视网膜母细胞瘤/癌基因/抑癌基因Key words
microRNAs/retinoblastoma/oncogenes/tumor suppressor gene引用本文复制引用
曾静,唐瑞雪,何融泉,陈罡..MicroRNAs在视网膜母细胞瘤的研究新进展[J].国际眼科杂志,2014,(11):1995-1998,4.基金项目
广西壮族自治区卫生厅科研课题(No. Z2008159)@@@@ Guangxi Zhuang Autonomous Region Health Department Research Projects (No. Z2008159) （No. Z2008159）
