国际眼科杂志Issue(1)：162-164,3.DOI:10.3980/j.issn.1672-5123.2015.1.49
伴有下斜肌功能亢进外斜V征眼外肌myogenin的研究
Muscular expression of myogenin in V-pattern exotropia with inferior oblique overaction patients
任晔 1严宏2
作者信息
- 1. 710054 中国陕西省西安市卫生学校
- 2. 710038 中国陕西省西安市，第四军医大学唐都医院眼科
- 折叠
摘要
Abstract
Abstract•AlM: To study the number of myogenin - positive activated satellite cells in the inferior oblique muscles and the medial muscles of V- pattern exotropia with inferior oblique overaction, to further explore the possible etiological factors of V-pattern exotropia with inferior oblique overaction.• METHODS: The inferior oblique muscles and the medial muscles were cut from V - pattern exotropia patients with inferior oblique overaction during strabismus operation treated as the strabismus group. Cross sections were stained immunohistochemically for the presence of activated satellite cells, as identified by myogenin immunoreactivity. The inferior oblique muscles and the medial muscles were obtained from the corneal transplant donors ( six eyes of six cases) , which treated as the control group.• RESULTS: The frequency of myogenin - positive satellite cells of the inferior oblique muscles was (22. 7± 7.03)% and (4. 2±0. 75)% in the strabismus group and the control group. Significant differences existed in the expression of myogenin in two groups (P<0. 05). Again, the frequency of myogenin-positive satellite cells of the medial muscles was (2. 2±0. 75)% and (4. 5±1. 05)% in the strabismus group and the control group. Significant differences also existed in the expression of myogenin in two groups (P<0. 05).•CONCLUSlON: lt is first report that myogenin-positive satellite cells presents in extraocular muscles of V -pattern exotropia with inferior oblique overaction. The current results suggest that myogenin is one of possible etiological factors of V-pattern exotropia with inferior oblique overaction.关键词
外斜V征/下斜肌/内直肌/myogeninKey words
•KEYWORDS：V - pattern exotropia/inferior oblique muscle/medial muscle/myogenin引用本文复制引用
任晔,严宏..伴有下斜肌功能亢进外斜V征眼外肌myogenin的研究[J].国际眼科杂志,2015,(1):162-164,3.
