国际眼科杂志Issue(2)：223-227,5.DOI:10.3980/j.issn.1672-5123.2015.2.10
年龄相关性黄斑变性流行病学研究进展
New research progress on the epidemiology of age - related macular degeneration
摘要
Abstract
Age-related macular degeneration ( AMD ) is a kind of age-related blinding degenerative fundus lesions, totally about 30 million patients suffering from AMD all over the world, with about 500 000 people blind for it yearly. As the development of economy and the aging of the population intensified, incidence of AMD indicates a trend of rising year by year, being the third major cause of blindness in our country. At present, the pathogenesis of AMD is not fully clear, as reported it may be related to oxidative stress, inflammatory immune response, VEGF and genetic manipulation. Clinical treatments mainly include photodynamic therapy, drug therapy, radiation therapy, laser photocoagulaory operation, the pupil warm treatments, Chinese medicine and intravitreous injection VEGF antagonists such as Ranibizumab, Conbercept and so on. ln this issue, we mainly expound on the progress in the epidemiological studies of AMD, especially elaborate the progress made on genetic manipulation in recent years.关键词
年龄相关性黄斑变性/流行病学/遗传调控Key words
age - related macular degeneration/epidemiology/genetic manipulation引用本文复制引用
武明星,郑政,周希瑗..年龄相关性黄斑变性流行病学研究进展[J].国际眼科杂志,2015,(2):223-227,5.基金项目
国家自然科学基金资助( No.81170858)@@@@National Natural Science Foundation of China (No.81170858) （ No.81170858）
