国际眼科杂志Issue(3)：448-450,3.DOI:10.3980/j.issn.1672-5123.2015.3.18
α晶体蛋白在视神经损伤后再生中的作用研究进展
Research progress of α-crystaIIin in regeneration of optic nerve injury
摘要
Abstract
·α-crystallin is the predominant structural protein in the lens.lt is a member of small heat shock proteins ( sHSPs) which has the common functions of HSPs.lt also has anti-apoptotic activity etc.Recently, it has been proved to combine with the cellular membrane of retinal ganglion cells ( RGCs ) to enhance the survival of RGCs and the regeneration of axons, thereby partly restore visual function.But we haven’t come to a unified conclusion of the mechanism.This review is focused on structure and functions of α-crystallin, the protection function and mechanism of α-crystallin towards RGCs after the optic nerve injury.关键词
α晶体蛋白/视神经损伤/再生/视网膜神经节细胞Key words
α-crystallin/optic nerve injury/regeneration/retinal ganglion cells引用本文复制引用
李贇婷,曹霞,马林昆..α晶体蛋白在视神经损伤后再生中的作用研究进展[J].国际眼科杂志,2015,(3):448-450,3.基金项目
国家自然科学地区基金（ No．31160206）；云南省联合重点专项 （）
