国际眼科杂志Issue(4):633-635,3.DOI:10.3980/j.issn.1672-5123.2015.4.16
鼠神经生长因子对外伤性视神经病变治疗作用的 Meta分析
Treatment for traumatic optic neuropathy with mouse nerve growth factor:a meta-analysis
刘静雯 1秦波2
作者信息
- 1. 510632 中国广东省广州市,暨南大学第二临床医学院
- 2. 518000 中国广东省深圳市,暨南大学附属深圳眼科医院 深圳市眼科医院
- 折叠
摘要
Abstract
AIM:To evaluate the efficacy of treating traumatic optic neuropathy( TON) with mouse nerve growth factor. <br> METHODS: We searched the Cochrane Library, Pubmed, Medline, CNKI, Wanfang database and VIP to collect randomized controlled trials ( RCTs ) of using mouse nerve growth factor for TON. The quality of the included trials was assessed and poor-qualified trials were eliminated before the meta - analysis was conducted. <br> RESULTS:Seven RCTs with a total of 399 eyes included were retrieved, and OR=3. 78 with a 95%CI of [ 2. 35, 6.06], the difference was significant (P<0. 01). <br> CONCLUSION:The existing evidence supports that the prognosis of TON is better when mouse nerve growth factor are adopted in treatment, but there is still a need for well-planned, large-scale and multicenter RCTs to verify it.关键词
鼠神经生长因子/外伤性视神经病变/Meta分析Key words
mouse nerve growth factor/traumatic optic neuropathy/meta-analysis引用本文复制引用
刘静雯,秦波..鼠神经生长因子对外伤性视神经病变治疗作用的 Meta分析[J].国际眼科杂志,2015,(4):633-635,3.