国际眼科杂志Issue(5)：745-749,5.DOI:10.3980/j.issn.1672-5123.2015.5.01
原发性开角型青光眼和高眼压患者及正常人群结膜印迹细胞学检查的比较
Comparison of conjunctival impression cytology in primary open angle glaucoma, ocular hypertension and normal subjects
Ufuk Elgin 1Mehmet Citirik 1Hulya Haksever 2Emine Sen 1Faruk Ozturk 1Huseyin Ustun2
作者信息
- 1. 土耳其，安卡拉06240，安卡拉Ulucanlar眼研究医院眼科
- 2. 土耳其，安卡拉06340，安卡拉培训与研究医院病理科
- 折叠
摘要
Abstract
•AlM:To compare the tear functions and the impression cytology scores of the patients with primary open angle glaucoma ( POAG ) , ocular hypertension ( OHT ) and normal subjects with healthy ocular surface both functionally and clinically. <br> •METHODS: Eleven eyes of 11 patients with POAG (mean age: 62. 7±6. 1y), 12 eyes of 12 patients ( mean age:62. 8±6. 4y ) with OHT and 12 eyes of 12 normal subjects ( mean age: 62. 9±6. 03y) were included to this prospective study. The patients with POAG and OHT had been recently diagnosed with these diseases and none of them had taken anti - glaucoma treatment before. ln addition to conjunctival impression cytology, tear break-up time ( TBUT ) and basal Schirmer’s tests ( BST ) were performed. lmpression cytology specimens of each group were graded and scored in the range of 0-3 according to Nelson’s method. Kruskal- Wallis analysis and Dunn’s multiple comparison tests were used for statistical analysis. <br> •RESULTS:The mean BST values were 10. 4±1. 3, 10. 9±1. 2 and 11. 1±1. 1 mm/5min of POAG, OHT and control groups respectively. The differences among the BST values of the POAG, OHT and control group were not statistically significant (P=0. 33). The mean TBUT values were 11. 2±1. 1, 11. 3±1. 1 and 11. 8±1. 2s in POAG, OHT and normal subjects respectively. The differences among the BUT values of the POAG, OHT and control group were not statistically significant (P=0. 35). Six eyes (54. 5%) revealed grade 0 and 5 eyes ( 45. 5%) revealed grade 1 impression cytology scores in POAG group. Six eyes (50%) revealed grade 0 and 6 eyes (50%) revealed grade 1 impression cytology scores in OHT group and 6 eyes (50%) revealed grade 0 and 6 eyes (50%) revealed grade 1 impression cytology scores in normal subjects ( P =0. 97). <br> •CONCLUSlON: Oxidative stress may cause glaucoma, ocular surface diseases, lacrimal gland malfunction and a decrease in mucus secretion ofgoblet cells in all of the body. There were no significant differences between the impression cytology scores of patients with POAG, OHT and normal subjects.关键词
结膜印迹细胞学/原发性开角型青光眼/高眼压Key words
conjunctival impression cytology/primary open angle glaucoma/ocular hypertension引用本文复制引用
Ufuk Elgin,Mehmet Citirik,Hulya Haksever,Emine Sen,Faruk Ozturk,Huseyin Ustun..原发性开角型青光眼和高眼压患者及正常人群结膜印迹细胞学检查的比较[J].国际眼科杂志,2015,(5):745-749,5.
