中南医学科学杂志Issue(1)：45-48,4.DOI:10.15972/j.cnki.43-1509/r.2015.01.011
磁共振灌注成像在鼻咽癌放射治疗中的应用
Application of Magnetic Resonance Perfusion Weighted Imaging in Nasopharyngeal Carcinoma Radiotherapy
摘要
Abstract
Objective To study the application of magnetic resonance perfusion weighted imaging( MR-PWI) parame-ters as the feasibility of nasopharyngeal carcinoma radiotherapy sensitivity evaluation index,and its value in the follow-up after radiotherapy for nasopharyngeal carcinoma ( NPC) . Methods 64 cases of patients with nasopharyngeal carcinoma ( NPC), which were confirmed by histopathology,history of treated before are not radiotherapy or chemotherapy. The day before radio-therapy and radiotherapy after four weeks in a routine MRI and MR PWI inspection,comparison and analysis,the size of the tumor before and after radiotherapy of nasopharyngeal perfusion characteristics and changes of perfusion parameters. Result In the image of MR-PWI,before radiotherapy of nasopharyngeal mass mainly for high perfusion,it is high perfusion area bigger level display area is smaller than before radiotherapy enhanced T1WI fat suppression sequence(P<0. 05);After 40 Gy dose radiotherapy,high sensitive group significantly decreased perfusion area,high sensitive group significantly decreased perfusion area,its decline in area than enhanced T1WI fat suppression sequence,(P<0. 05). Conclusion Combined with perfusion imaging,can be more accurate reflection of biological changes after radiotherapy of nasopharyngeal carcinoma;perfusion image and its parameters in as evaluation index of nasopharyngeal carcinoma radiotherapy sensitivity,and the identification of tumor recurrence after radiotherapy and necrosis or fibrosis has important reference value.关键词
磁共振/灌注/鼻咽癌/放疗Key words
magnetic resonance/perfusion/nasopharyngeal carcinoma/radiotherapy分类
医药卫生引用本文复制引用
聂林,李庆,赵衡,周定中,刘进才..磁共振灌注成像在鼻咽癌放射治疗中的应用[J].中南医学科学杂志,2015,(1):45-48,4.基金项目
郴州市科技局资助(2011J169) （2011J169）
