南京师范大学学报（工程技术版）Issue(1)：73-77,5.
响应面优化野艾蒿二咖啡酰奎尼酸的高效提取
Optimization Extraction of Dicaffeoylquinic Acids from Artemisia lavandulaefolia DC. Using Response Surface Methodology
钱媛媛 1陈育如 1杨凤平 1柯小红 1闫莽 1唐超2
作者信息
- 1. 南京师范大学生命科学学院，江苏省微生物资源产业化工程技术研究中心，江苏省微生物与基因组学重点实验室，江苏省生物多样性与生物技术重点实验室，江苏 南京210023
- 2. 滇虹药业集团股份有限公司，云南 昆明650106
- 折叠
摘要
Abstract
Response surface methodology is applied to optimize the extraction conditions of diCQAs from Artemisia lavan-dulaefolia DC. The combined effects of independent variables ( ethanol concentration, extraction temperature, extraction time,solid-liquid ratio) are studied and the optimal extraction conditions are as follows:ethanol concentration 72%, extraction temperature 53 ℃,extraction time 102 min,solid-liquid ratio 1∶54 g/mL. Under these conditions,the yield of diCQAs is 3.30% and the extraction yield is 91%. The content of diCQAs(3,5-diCQA,4,5-diCQA,1,5-diCQA) are 14.2 mg/g,10.5 mg/g and 8.3 mg/g respectively,which are identified by LC/MS. A. lavandulaefolia DC. is the materials that rich in dicaffeoylquinic acids.关键词
野艾蒿/二咖啡酰奎尼酸/提取/响应面/LC/MSKey words
Artemisia lavandulaefolia DC./dicaffeoylquinic acids/extraction/response surface methodology/LC/MS分类
轻工纺织引用本文复制引用
钱媛媛,陈育如,杨凤平,柯小红,闫莽,唐超..响应面优化野艾蒿二咖啡酰奎尼酸的高效提取[J].南京师范大学学报（工程技术版）,2015,(1):73-77,5.
