农业环境科学学报Issue(6)：1047-1052,6.DOI:10.11654/jaes.2015.06.005
腈醛混合物对明亮发光杆菌联合毒性效应
Joint Toxicity of Cyanogenic Chemicals and Aldehydes to Photobacterium phosphoreum
摘要
Abstract
It is widely accepted that organisms are often exposed to mixtures of multiple pollutants rather than to single chemical in the envi-ronment, such as cyanogenic chemicals and aldehydes. The interactions among the components in the pollutant mixtures might cause sub-stantial changes in their apparent properties, leading to additive, synergistic or antagonistic effects, and thus posing potential threats on the environmental safety and human health. In this paper, cyanogenic chemicals and aldehydes were selected as the research chemicals and Photobacterium phosphoreum as a model organism. The acute toxicity of cyanogenic and aldehyde compounds to Photobacterium phospho-reum was tested based on the light emitting reaction in bioluminescence. General approaches were therefore proposed to predict the biologi-cal toxicity of chemical mixtures with different toxicity processes by using effective carbon charge and substituent constant. The QSAR mod-els for acute toxicity of cyanogenic chemicals and aldehydes alone and in mixture were established. The mechanisms of mixed toxicity of cyanogenic chemicals and aldehydes were suggested. Results demonstrated that the joint toxicity changed with different mixtures of cyanogenic chemicals and aldehydes, which showed additive and synergistic effects. This work would provide basic information for the joint ecological risk assessment and remediation of cyanogenic chemicals and aldehydes.关键词
腈类化合物/醛类化合物/明亮发光杆菌/急性联合毒性/QSAR模型Key words
cyanogenic chemicals/aldehyde compounds/Photobacterium phosphoreum/acute joint toxicity/QSAR model分类
资源环境引用本文复制引用
花文凤,田大勇,安情情,林志芬,张饮江..腈醛混合物对明亮发光杆菌联合毒性效应[J].农业环境科学学报,2015,(6):1047-1052,6.基金项目
国家自然科学面上基金（201177092）；同济大学污染控制与资源化研究国家重点实验室自主研究重点项目（PCR-RY11003）；高等学校博士学科点专项科研基金课题 （）
