农药学学报Issue(2)：220-224,5.DOI:10.3969/j.issn.1008-7303.2015.02.15
嘧啶联吡唑甲酰胺类化合物的合成及除草活性
Synthesis and herbicidal activity of novel pyrimidine substituted pyrazolecarboxamides
摘要
Abstract
A number of novel pyrimidine substituted pyrazolecarboxamides 5a-5o were synthesized, and their structures were confirmed by 1 H NMR and MS analysis. The preliminary herbicidal activity indicated that Stellaria media growth inhibition rate was over 90% for the compounds( R)-N-[1-(4-chlorophenyl ) ethyl ]-3-( difluoromethyl )-1-( 4 , 6-dimethoxypyrimidin-2-yl )-1 H-pyrazole-4-carboxamide ( 5 c ) , N-( 1-( 4-chlorophenyl ) ethyl )-1-( 4 , 6-dimethoxypyrimidin-2-yl )-N-methyl-3-( trifluoromethyl )-1 H-pyrazole-4-carboxamide ( 5 i ) and N-( 1-( 4-chlorophenyl ) ethyl )-1-( 4 , 6-dimethoxypyrimidin-2-yl)-3-( trifluoromethyl )-1 H-pyrazole-4-carboxamide ( 5 k ) by postemergence foliar spray processing at 150 g/hm2; and the compounds N-[ 1-( 4-chlorophenyl ) ethyl ]-3-( difluoromethyl )-1-( 4 , 6-dimethoxy-pyrimidin-2-yl )-1 H-pyrazole-4-carboxamide ( 5 b ) and 5 c showed inhibition rate of 100% against S. media by preemergence soil spray processing at the same dose. Compounds of this structure can be potentially used as lead compounds for herbicide.关键词
嘧啶联吡唑甲酰胺/合成/除草活性Key words
pyrimidine substituted pyrazolecarboxamides/synthesis/herbicidal activity分类
化学化工引用本文复制引用
彭雪琴,史建俊,彭伟立,唐伟,谭成侠..嘧啶联吡唑甲酰胺类化合物的合成及除草活性[J].农药学学报,2015,(2):220-224,5.基金项目
“十二五”国家科技支撑计划项目(2011BAE06B03-01) （2011BAE06B03-01）
